Smart and witty, this CBS sitcom chronicles the misadventures of Leonard and Sheldon, two brilliant-and socially awkward-college physicists who don't have a clue about anything except science. When pretty blonde Penny moves into the apartment across the hall, the guys enlist her help to learn about life outside of the lab. Johnny Galecki, Jim Parsons, Kaley Cuoco, Simon Helberg star.277 episodes on 25 discs. 94 2/3 hrs. Widescreen (Enhanced); Soundtrack: English Dolby Digital 5.1; Subtitles: English (SDH), French, Spanish; featurettes; gag reel.